Pro-Mind

PRO-MIND

Effect of probiotics on depressive symptoms in patients with gut-brain disorders: A probiotic-placebo comparison study

Structure

DURATION

26 MONTHS

BUDGET

€4.598.275,25

FUNDING

€1.989.276,01

Project mission

PRO-MIND is a collaborative project involving companies, hospitals, and research centres working together to identify a natural therapeutic solution for patients suffering from gastrointestinal disorders, who frequently experience comorbid mental health conditions. In this context, the project explores the use of optimized probiotic formulations to simultaneously target gastrointestinal disorders and depressive symptoms by modulating the gut–brain axis. Through pre-clinical and clinical studies, PRO-MIND will assess the products’ efficacy, tolerability, and impact on the microbiota and on inflammatory processes. By restoring gut microbiota balance and influencing pathways linked to mood regulation, these improved probiotic-based interventions could represent a safer alternative or complement to conventional antidepressant therapies. 

Project ID: ID 6107778  |  CUP Code: E49I25001460007

Project Partners

Opella.
Consorzio italbiotec
Bict
IRCCSISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Fondazione IRCCS San Gerardo dei Tintori
Università degli Studi di Milano
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Address

Registered office
Piazza della Trivulziana, 4/A
20126 Milan (IT)
Headquarters
Piazza della Trivulziana, 4/A
20126 Milan (IT)